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A review of 62 scientific studies published in Osteoporosis International found that microplastics weaken bones by disrupting bone marrow stem cells and stimulating osteoclasts, cells that degrade bone tissue. Laboratory experiments found the particles reduce cell viability, induce premature cellular aging, modify gene expression, and trigger inflammatory responses. Animal studies found microplastic accumulation decreases white blood cell counts and deteriorates bone microstructure, creating irregular cell structures that increase fracture risk. Rodrigo Bueno de Oliveira from the State University of Campinas in Brazil said the effects interrupted skeletal growth in test animals.

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Anthropic's Claude Sonnet 4.5 ran autonomously for 30 hours to build a chat application similar to Slack or Teams, generating approximately 11,000 lines of code before stopping upon task completion. The model, announced today, marks a significant leap from the company's Opus 4 model, which ran for seven hours in May. Claude Sonnet 4.5 performs three times better at browser navigation and computer use than Anthropic's October technology. Beta-tester Canva deployed the model for complex engineering tasks in its codebase and product features. Anthropic paired the release with virtual machines, memory, context management, and multi-agent support tools, enabling developers to build their own AI agents using the same building blocks that power Claude Code.

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An anonymous reader writes: Landlords are using a service that logs into a potential renter's employer systems and scrapes their paystubs and other information en masse, potentially in violation of U.S. hacking laws, according to screenshots of the tool shared with 404 Media. The screenshots highlight the intrusive methods some landlords use when screening potential tenants, taking information they may not need, or legally be entitled to, to assess a renter. "This is a statewide consumer-finance abuse that forces renters to surrender payroll and bank logins or face homelessness," one renter who was forced to use the tool and who saw it taking more data than was necessary for their apartment application told 404 Media. 404 Media granted the person anonymity to protect them from retaliation from their landlord or the services used. [...] "Argyle hijacked my live Workday session, stayed hidden from view, and downloaded every pay stub plus all W-4s back to 2024, each PDF seconds apart," they said. "Workday audit logs show dozens of 'Print' events from two IPs from a MAC which I do not use," they added, referring to a MAC address, a unique identifier assigned to each device on a network.

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An anonymous reader shares a report: You've probably heard of vibe coding -- novices writing apps by creating a simple AI prompt -- but now Microsoft wants to introduce a similar thing for its Office apps. The software maker is launching a new Agent Mode in Excel and Word that can generate complex spreadsheets and documents with just a prompt. A new Office Agent in Copilot chat, powered by Anthropic models, is also launching today that can create PowerPoint presentations and Word documents from a "vibe working" chatbot. [...] Agent Mode essentially takes a complex task and breaks it down with planning and reasoning that you can follow. It then uses OpenAI's GPT-5 model to break down each step of document creation into an agentic task and execute it. It's like watching an automated macro in real time, showing everything it's doing in the sidebar.

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The world's highest bridge opened in China on Sunday, taking the crown from another bridge in the same province. From a report: The Huajiang Grand Canyon Bridge soars about 2,050 feet above a river and gorge in the southern Chinese province of Guizhou. It is more than twice as high as the Royal Gorge Bridge, which is suspended 956 feet above the Arkansas River in Colorado and is the highest in the United States. According to Chinese state media, the new Guizhou bridge also sets a record as the world's longest bridge in a mountainous region, spanning 4,600 feet across. Hailed as China's latest "infrastructure miracle," the bridge is designed to spur tourism and economic growth in one of the country's least developed regions.

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