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Stanford researchers have developed a blood-based AI tool that calculates the biological age of individual organs to reveal early signs of aging-related disease. The Mercury News reports: The tool, unveiled in Nature Medicine Wednesday, was developed by a research team spearheaded by Tony Wyss-Coray. Wyss-Coray, a Stanford Medicine professor who has spent almost 15 years fixated on the study of aging, said that the tool could "change our approach to health care." Scouring a single draw of blood for thousands of proteins, the tool works by first comparing the levels of these proteins with their average levels at a given age. An artificial intelligence algorithm then uses these gaps to derive a "biological age" for each organ.
To test the accuracy of these "biological ages," the researchers processed data for 45,000 people from the UK Biobank, a database that has kept detailed health information from over half a million British citizens for the last 17 years. When they analyzed the data, the researchers found a clear trend for all 11 organs they studied; biologically older organs were significantly more likely to develop aging-related diseases than younger ones. For instance, those with older hearts were at much higher risk for atrial fibrillation or heart failure, while those with older lungs were much more likely to develop chronic obstructive pulmonary disease.
But the brain's biological age, Wyss-Coray said, was "particularly important in determining or predicting how long you're going to live." "If you have a very young brain, those people live the longest," he said. "If you have a very old brain, those people are going to die the soonest out of all the organs we looked at." Indeed, for a given chronological age, those with "extremely aged brains" -- the 7% whose brains scored the highest on biological age -- were over 12 times more likely to develop Alzheimer's disease over the next decade than those with "extremely youthful brains" -- the 7% whose brains inhabited the other end of the spectrum.
Wyss-Coray's team also found several factors -- smoking, alcohol, poverty, insomnia and processed meat consumption -- were directly correlated with biologically aged organs. Poultry consumption, vigorous exercise, and oily fish consumption were among the factors correlated with biologically youthful organs. Supplements like glucosamine and estrogen replacements also seemed to have "protective effects," Wyss-Coray said. [...] The test ... would cost $200 once it could be operated at scale.
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joshuark writes: A Russian basketball player, Daniil Kasatkin, was arrested on June 21 in France at the request of the United States as he allegedly is part of a network of hackers. Daniil Kasatkin, aged 26, is accused by the United States of negotiating the payment of ransoms to this hacker network, which he denies. He has been studied in the United States, and is the subject of a U.S. arrest warrant for "conspiracy to commit computer fraud" and "computer fraud conspiracy."
His lawyer alleges that Kasatkin is not guilty of these crimes and that they are instead linked to a second-hand computer that he purchased. "He bought a second-hand computer. He did absolutely nothing. He's stunned," his lawyer, Freric Belot, told the media. "He's useless with computers and can't even install an application. He didn't touch anything on the computer: it was either hacked, or the hacker sold it to him to act under the cover of another person." The report notes that Kasatkin briefly played NCAA basketball at Penn State before returning to Russia in 2019. He also appeared in 172 games with MBA-MAI before he left the team.
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iFixit has harsh words for Nintendo's $85 Switch 2 Pro controller, calling it a "piss-poor excuse for a controller" due to its difficult repairability, use of outdated drift-prone joysticks, and poor internal accessibility. The Verge reports: Opening the controller requires you to first forcefully remove a faceplate held in place by adhesive tape before a single screw is visible. But you'll need to extract several other parts and components, including the controller's mainboard, before its battery is even accessible. As previously revealed, the Pro 2 is still using older potentiometer-based joysticks that are prone to developing drift over time. They do feature a modular design that will potentially make them easier to swap with third-party Hall effect or TMR replacements, but reassembling the controller after that DIY upgrade will require you to replace all the adhesive tape you destroyed during disassembly. You can watch the full teardown on YouTube.
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An anonymous reader quotes a report from Bloomberg: JPMorgan Chase has told financial-technology companies that it will start charging fees amounting to hundreds of millions of dollars for access to their customers' bank account information -- a move that threatens to upend the industry's business models. The largest US bank has sent pricing sheets to data aggregators -- which connect banks and fintechs -- outlining the new charges, according to people familiar with the matter. The fees vary depending on how companies use the information, with higher levies tied to payments-focused companies, the people said, asking not to be identified discussing private information.
A representative for JPMorgan said the bank has invested significant resources to create a secure system that protects consumer data. "We've had productive conversations and are working with the entire ecosystem to ensure we're all making the necessary investments in the infrastructure that keeps our customers safe," the spokesperson said in a statement. The fees -- expected to take effect later this year depending on the fate of a Biden-era regulation -- aren't final and could be negotiated. [The open-banking measure, finalized in October, enables consumers to demand, download and transfer their highly-coveted data to another lender or financial services provider for free.]
The charges would drastically reshape the business for fintech firms, which fundamentally rely on their access to customers' bank accounts. Payment platforms like PayPal's Venmo, cryptocurrency wallets such as Coinbase and retail-trading brokerages like Robinhood all use this data so customers can send, receive and trade money. Typically, the firms have been able to get it for free. Many fintechs access data using aggregators such as Plaid and MX, which provide the plumbing between fintechs and banks. The new fees -- which vary from firm to firm -- could be passed from the aggregators to the fintechs and, ultimately, consumers. The aggregator firms have been in discussions with JPMorgan about the charges, and those talks are constructive and ongoing, another person familiar with the matter said.
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No reason given for the 6% cull, but the CEO has previously talked up AI taking jobs
Recruit Holdings, the Japanese job site conglomerate that owns recruitment job site Indeed and employer reviewer Glassdoor, has eliminated about 1,300 positions.…
OpenAI's planned acquisition of Windsurf has fallen apart. Instead, Google is hiring Windsurf CEO Varun Mohan, cofounder Douglas Chen, and parts of its R&D team to join DeepMind and focus on agentic coding for Gemini. Google will not acquire Windsurf but will receive a non-exclusive license to some of its technology, while Windsurf continues independently under new leadership. The Verge reports: Effective immediately, Jeff Wang, Windsurf's head of business, has become interim CEO, and Graham Moreno, its VP of global sales, will be Windsurf's new president. "Gemini is one of the best models available and we've been investing in its advanced capabilities for developers," Chris Pappas, a spokesperson for Google, told The Verge in a statement. "We're excited to welcome some top AI coding talent from Windsurf's team to Google DeepMind to advance our work in agentic coding."
"We are excited to be joining Google DeepMind along with some of the Windsurf team," Mohan and Chen said in a statement. "We are proud of what Windsurf has built over the last four years and are excited to see it move forward with their world class team and kick-start the next phase." Google didn't share how much it was paying to bring on the team. OpenAI was previously reported to be buying Windsurf for $3 billion.
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Predicted a 24% boost, but clocked a 19% drag
Artificial intelligence coding tools are supposed to make software development faster, but researchers who tested these tools in a randomized, controlled trial found the opposite.…
BYD has unveiled fully autonomous Level 4 self-parking across its vehicle lineup, powered by its advanced multi-sensor "God's Eye" system that's used by more than 1 million cars across China. "The company is so confident in the technology that it announced that it will cover any damages to your car or any other vehicle if things go wrong," adds Fast Company. "This means if anything happens, the owner won't have to file a claim and have their premiums go up." From the report: BYD's confidence stems from a sophisticated sensor architecture. The God's Eye system deploys multiple sensing technologies working in concert, unlike Tesla's problematic camera-only approach. Even the entry-level God's Eye C variant -- one of three autonomous driving levels included in most affordable models -- includes 12 cameras, 5 millimeter-wave radars, and 12 ultrasonic sensors with 1-centimeter accuracy. The mid-tier God's Eye B adds a lidar sensor, while the premium God's Eye A variant features three lidar sensors for maximum precision.
The system's parking accuracy allows the car to get within 0.8 inches of other objects, enabled by multiple redundant sensors that create a three-dimensional map. This allows the vehicle a deep understanding of its environment. This multi-sensor approach allows the system to detect obstacles. It can even recognize hanging objects over the roof line of the car.
The company reports that more than 1 million vehicles now carry the God's Eye system, an impressive deployment scale that starts with the most inexpensive models, like the $9,550 BYD Seagull, and go all the way to the $236,000 BYD Yangwang U9, a hypercar that can detect potholes on the road and jump over them. Yes. If the God's Eye detects an obstacle on the road, it will literally jump over it.
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An anonymous reader quotes a report from Ars Technica: For the second time in a year, Google has announced that it will render some of its past phones almost unusable with a software update, and users don't have any choice in the matter. After nerfing the Pixel 4a's battery capacity earlier this year, Google has now confirmed a similar update is rolling out to the Pixel 6a. The new July Android update adds "battery management features" that will make the phone unusable. Given the risks involved, Google had no choice but to act, but it could choose to take better care of its customers and use better components in the first place. Unfortunately, a lot more phones are about to end up in the trash. [...]
Pixel 4a units contained one of two different batteries, and only the one manufactured by a company called Lishen was downgraded. For the Pixel 6a, Google has decreed that the battery limits will be imposed when the cells hit 400 charge cycles. Beyond that, the risk of fire becomes too great -- there have been reports of Pixel 6a phones bursting into flames. Clearly, Google had to do something, but the remedies it settled on feel unnecessarily hostile to customers. It had a chance to do better the second time, but the solution for the Pixel 6a is more of the same. [...]
When Google killed the Pixel 4a's battery life, it offered a few options. You could have the battery replaced for free, get $50 cash, or accept a $100 credit in the Google Store. However, claiming the money or free battery was a frustrating experience that was rife with fees and caveats. The store credit is also only good on phones and can't be used with other promotions or discounts. And the battery swap? You'd better hope there's nothing else wrong with the device. If it has any damage, like cracked glass, it may not qualify for a free battery replacement.
Now we have the Pixel 6a Battery Performance Program with all the same problems. Pixel 6a owners can get $100 in cash or $150 in store credit. Alternatively, Google offers a free battery replacement with the same limits on phone condition. This is all particularly galling because the Pixel 6a is still an officially supported phone, with its final guaranteed update coming in 2027. Google also pulled previous software packages for this phone to prevent rollbacks. [...] If you have a Pixel 6a, the battery-killing update is rolling out now. You'll have no choice but to install it if you want to remain on the official software. Google has a support site where you can try to get a free battery swap or some cash.
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Apple added the 2013 "Trash Can" Mac Pro to its vintage products list alongside the 2019 13-inch MacBook Air, 2019 iMac, 2018 iPad Pro models, and the 128GB iPhone 8. The cylindrical Mac Pro remained on sale until December 2019, when Apple replaced it with the redesigned "Cheese Grater" model.
Products typically reach vintage status five years after their last distribution date. The 2013 Mac Pro's radical cylindrical design prevented internal component upgrades and created thermal limitations that Apple acknowledged in 2017. "I think we designed ourselves into a bit of a thermal corner," Apple hardware chief Craig Federighi said at the time.
Apple also moved several AirPort devices to its obsolete list, including the second-generation AirPort Express and AirPort Time Capsules. The 2013 Mac Pro's radical design created thermal limitations that Apple acknowledged in 2017.
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An announcement so weird it could only come from the Trump administration
video Flanked by a pair of buzzing drones that threatened to drown out his voice, US Secretary of Defense Pete Hegseth reached up to grab a memorandum hung from a third drone hovering above his head. …
The U.S. government has canceled a proposed $900 million project to study in unprecedented detail the afterglow of the Big Bang, the cosmic microwave background (CMB) radiation. Science magazine: Known as CMB-S4, the project envisioned new arrays of ultrasensitive microwave telescopes at the South Pole and in Chile's Atacama Desert. Their goal: to detect patterns in the ancient light that would prove the newborn universe expanded in an exponential growth spurt called cosmic inflation.
The project, which could have delivered smoking gun evidence for a key theory in cosmology, was supposed to be a joint venture between the National Science Foundation (NSF) and the Department of Energy (DOE). However, yesterday, the agencies sent an unsigned statement to the leaders of the collaboration saying the project is off. "DOE and NSF have jointly decided that they can no longer support the CMB-S4 Project," it reads.
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Data poisoning, meet data detox
ai-pocalypse Computer scientists say they've devised a way to remove image-based protection mechanisms developed to protect artists from unwanted use of their work for AI training.…
An anonymous reader shares a report: This week has seen the shortest days of the year so far. According to data from the U.S. Naval Observatory and the International Earth Rotation and Reference Systems Service, Tuesday's rotation was about 1.34 milliseconds less than 24 hours. More quick spins are expected this week, later this month and in early August, according to predictions from the website Time and Date.
This isn't completely out of the ordinary: Our world's spins have been faster than usual lately. The average day has mostly shortened over the past decade, and within the past five years or so, the full rotation has clocked in at a hair less than 24 hours more often than not. Factors driving the change include movements at Earth's core, atmospheric changes and the moon's position.
But long-term trends do not suggest that the days will shorten in perpetuity. In fact, it is just the opposite. For many millenniums, the days have been growing longer. A Tyrannosaurus rex that lived 70 million years ago would have experienced an average daily rotation of about 23 1/2 hours, studies have found.
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Denmark's Parliament adopted a law in May raising the retirement age to 70 by 2040, up from the current 67, affecting anyone born after December 31, 1970. The country indexed its official retirement age to life expectancy in 2006 and revises it every five years, with the age set to increase to 68 in 2030 and 69 in 2035.
Few Danes actually work until the legal retirement age -- in 2022, when the official age was 67, the actual average retirement age was around 64, according to the Organization for Economic Cooperation and Development. About 20% of Danish retirees leave work because they cannot find employment or are too sick to continue. The universal public pension currently provides 7,198 kroner ($1,130) per month, supplemented by mandatory and optional employer-funded pensions.
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As allegations fly regarding fraudulent powers of attorney, one member wants to wind up AFRINIC and start again
The receiver of the African Network Information Center (AFRINIC) has not explained why he chose to annul its recent election, prompting ICANN to again warn that it may need to step in, and longtime AFRINIC litigant Cloud Innovation to call for the body to be wound up.…
Four years of research following the 2021 western North American heat wave has revealed both the meteorological conditions that fuel extreme temperatures and evidence that heat has physical limits. The 2021 event "shocked everyone, including specialists working on the subject. People were completely stunned," said Robin Noyelle, a postdoctoral researcher in climate science at ETH Zurich.
Scientists now focus on temperature departures from local averages rather than absolute readings. The most anomalously warm temperature was recorded in Antarctica, where temperatures rose 39C above average in March 2022. North Pole temperatures surged 20C higher than normal in February, reaching the melting point in winter.
Research has identified five key factors that enable extreme heat: cloudless skies, high pressure, dark surfaces, lower altitudes, and lack of water. "Basically all of these conditions are met in Death Valley, but not in many other places in the world," said climate scientist Friederike Otto. Scientists insist that there are heat limits, though these upper bounds will rise with global warming, they caution.
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Intruders looked up how to use curl mid-attack - rookie errors kept damage minimal
Huntress security researchers observed exploitation of the CVSS 10.0 remote code execution (RCE) flaw in Wing FTP Server on July 1, just one day after its public disclosure.…
Warner Bros. releases a $225 million Superman reboot this week that executives consider the studio's final chance to build a successful cinematic universe rivaling Marvel's dominance. The film, written and directed by James Gunn, serves as the foundation for DC Studios' planned expansion into multiple films and television shows.
Warner Bros. Discovery CEO David Zaslav appointed Gunn and producer Peter Safran to lead the newly unified DC Studios in 2022, ending decades of corporate infighting that prevented the company's superheroes from matching Marvel's success. The Disney-owned Marvel Cinematic Universe has generated $32 billion across 36 films since 2008. Warner executives want the movie to gross over $500 million globally, according to WSJ. If successful, this would mark the first year since 2008 that DC outperforms Marvel at the box office.
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Hush-hush settlement follows decision to wind down PeopleSoft support
Enterprise software support giant Rimini Street has entered into a confidential settlement agreement with Oracle, signaling the two companies may be nearing the end of their long-running legal dispute.…
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