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An anonymous reader quotes a report from NPR: Chinese scientists have published the first report in a scientific journal of an attempt to use CRISPR-edited cells in a patient -- a 27-year-old man who is HIV-positive. While the treatment did not rid the man of the AIDS virus, the researchers and others are calling the report promising. That's because it indicates that so far the gene-editing technique seems to safely and effectively make the precise DNA change intended. The case was published in the New England Journal of Medicine. In the new report, the researchers attempted to use CRISPR to recreate the experiences of two men known as the Berlin patient and the London patient. In those cases, HIV-positive men were declared effectively cured after they received stem cell transplants from people born with variations of a gene known as CCR5 that makes people naturally resistant to HIV. The variation disables a molecular gateway HIV uses to enter and destroy key immune system cells. In the new case, [Hongkui Deng, a professor of cell biology at the Peking University] and his colleagues used CRISPR to edit the CCR5 gene on stem cells to recreate the naturally occurring protection against HIV. They then used the edited cells to perform a stem cell transplant for the patient. The man also had acute lymphoblastic leukemia, a form of blood cancer. The transplant appears to have put the patient's leukemia into remission, the researchers reported. He suffered no apparent adverse side effects from the gene-edited cells, which have persisted in his body for more than 19 months, according to the report. "The approach did not reduce levels of HIV in the man's body because only about 5% of his white blood cells carried the edited CCR5 variation," the report adds. "So Deng says his team plans to focus on finding ways to boost that closer to 100%, which is what would be needed to eradicate the virus." Regardless, the findings are important positive outcomes that suggest the approach is safe and could work.

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In new research published on Thursday in the journal Joule, Dr. Raman, an electrical engineer at the University of California, Los Angeles, demonstrated a way to harness a dark night sky to power a light bulb. The New York Times reports: His prototype device employs radiative cooling, the phenomenon that makes buildings and parks feel cooler than the surrounding air after sunset. As Dr. Raman's device releases heat, it does so unevenly, the top side cooling more than the bottom. It then converts the difference in heat into electricity. In the paper, Dr. Raman described how the device, when connected to a voltage converter, was able to power a white LED. The prototype built by Dr. Raman resembles a hockey puck set inside a chafing dish. The puck is a polystyrene disk coated in black paint and covered with a wind shield. At its heart is an off-the shelf gadget called a thermoelectric generator, which uses the difference in temperature between opposite sides of the device to generate a current. A similar device powers NASA's Curiosity rover on Mars; its thermoelectric generator derives heat from plutonium radiation. Usually, the temperature difference in these generators is stark, and they are carefully engineered to separate hot and cold. Dr. Raman's device instead uses the atmosphere's ambient temperature as the heat source. The shift from warm to cool is very slight, meaning the device can't produce much power. His puck-in-a-dish is elevated on aluminum legs, enabling air to flow around it. As the dark puck loses warmth to the night sky, the side facing the stars grows colder than the side facing the air-warmed tabletop. This slight difference in temperature generates a flow of electricity. When paired with a voltage converter, the prototype produced 25 milliwatts of power per square meter. That is about three orders of magnitude lower than what a typical solar panel produces, and well short of even the roughly 4-watt maximum efficiency for such devices. Still, several experts said the prototype was an important contribution to a new and relatively unusual space in the renewable energy sector.

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Huawei is now selling the Matebook 13, Matebook 14, and Matebook X Pro to consumers in China with Deepin Linux preinstalled. "Deepin is a Chinese-domestic distribution, with their own desktop environment -- appropriately also called Deepin," notes TechRepublic. From the report: Huawei is passing along the savings to consumers as well, with the Matebook 13 and 14 models receiving a 300 yuan ($42 USD) price cut, though the Linux version of the MateBook X Pro is listed at 600 yuan ($84) higher. This pricing should be considered tentative, as the products are listed on VMALL, Huawei's ecommerce marketplace in China, though only allow users to be notified when they are in stock. It is possible that Huawei may lose the ability to purchase Windows licenses from Microsoft due to their placement on the "entity list," restricting companies dealing in U.S.-origin technology from conducting business with Huawei, constituting an effective blacklisting by the U.S. government. Sales of Linux laptops to consumers -- by Huawei, and in general -- could result in better driver support for fingerprint readers and other hardware with inconsistent Linux support. Huawei has yet to announce any Linux versions available in the West.

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Blokes left in legal limbo amid electronic records audit

Updated Two men hired to assess a court record system's computer security were arrested Wednesday – after they were caught physically sneaking into a courthouse.…

Red Hat developer Matthias Clasen has announced the release of GNOME 3.34, bringing many performance improvements and better Wayland support. Phoronix reports: Making GNOME 3.34 particularly exciting is the plethora of optimizations/fixes in tow with this six-month update. Equally exciting are a ton of improvements and additions around the Wayland support to ensure its performance and feature parity to X11. GNOME 3.34 also brings other improvements like sandboxed browsing with Epiphany, GNOME Music enhancements, GNOME Software improvements, and a ton of other refinements throughout GNOME Shell, Mutter, and the many GNOME applications. More details can be found via release announcement and release notes.

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An anonymous reader quotes a report from Ars Technica: AT&T expects to lose about 1.1 million TV customers in the third quarter as it faces pressure from an investment group that says AT&T's increased focus on the TV business was a giant mistake. In an update to shareholders yesterday, AT&T CFO John Stephens "said the company expects an incremental 300,000 to 350,000 premium video losses above the previous quarter's premium video results," according to AT&T. Since that's an incremental increase over the previous quarter's loss, that will amount to a three-month loss of more than 1 million TV customers. In Q2 2019, AT&T reported a net loss of 778,000 subscribers in the "Premium TV" category, which includes its DirecTV satellite and U-verse wireline TV services. With AT&T expecting to lose that amount of subscribers plus another 300,000 to 350,000, the update to shareholders suggests the Q3 loss in the category will be between 1,078,000 and 1,128,000 subscribers. (An AT&T spokesperson confirmed to Ars that a projected loss of 1,078,000 and 1,128,000 subscribers in Q3 is accurate.) AT&T's update to shareholders attributed the expected loss to "aggressively managing costs with retransmission negotiations, some of which resulted in content provider blackouts; and from limiting promotional pricing." AT&T said it has been "holding a hard line in negotiations" with programmers to control costs, but the resulting blackouts of channels is driving TV subscribers away. What's not included in the projected loss is AT&T TV Now (formerly known as DirecTV Now). "AT&T also lost 168,000 subscribers of DirecTV Now/AT&T TV Now in the second quarter, but it didn't say how that service will fare in the third quarter," the report adds.

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Bug-hunter says Cupertino won't even pay $1 reward for security hole

Video Apple's latest iOS 13 build appears to have the same sort of lock-screen bypass that plagued previous versions of the iPhone firmware.…

MojoKid writes: Gamer-targeted smartphones are beginning to pop up more often now, with devices like the Razer Phone 2, Xiaomi Black Shark, and the ASUS ROG Phone making waves in the market with performance enthusiasts. The latest release from ASUS, the ROG Phone II sports a specially binned chip from Qualcomm called the Snapdragon 855+. The higher performance SoC sports an octa-core CPU clocked at 2.96GHz, paired with an overclocked Adreno 640 GPU that can boost its performance up to 15 percent above spec. A generous 12GB of RAM, 1TB of storage and a 120Hz 6.59 FHD display trim out the rest of the ASUS ROG Phone II's specs. In addition, an enhanced on-board cooling system features a 3D vapor chamber, heat spreaders, and cooling pads that efficiently dissipate heat from inside the phone to the outside. It is designed to be above spec for the Snapdragon 855 chipset and necessary to keep 855+ stable during long gaming sessions. In benchmark testing, there's no question these system upgrades put up significantly better numbers than the average high-end Android phone on the market these days, such that the phone is about 10% faster than devices like Samsung's Galaxy Note 10 or the OnePlus 7 Pro. The ASUS ROG Phone II will be available later this month but pricing is still being determined.

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The remains of a man who went missing two decades ago in Florida have been found in a submerged car visible on Google Maps. The BBC reports: William Moldt, 40, was reported missing from Lantana, Florida, on November 7, 1997. He failed to return home from a night out at a club when he was 40 years old. A missing person investigation was launched by police but the case went cold. On August 28 this year -- 22 years on -- police were called to reports of a car found in a pond in Moon Bay Circle, Wellington. When the vehicle was pulled from the water, skeletal remains were found inside. One week later the remains were positively identified as belonging to Mr Moldt. A report by the Charley Project, an online database of cold cases in the U.S., said "a property surveyor saw the car while looking at Google Earth." "Amazingly, a vehicle had plainly [been] visible on a Google Earth satellite photo of the area since 2007, but apparently no-one had noticed it until 2019," according to the report. What appears to be a silver car submerged in the pond can still be viewed on Google Maps.

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But Trump Administration seemingly unbothered

After months of speculation about who exactly was behind a series of eavesdropping fake cell towers in Washington DC, it appears the answer is Israel.…

Irreparably damaged your phone in a freak accident? Not to worry -- Google's got your back. From a report: The search giant today announced that subscribers to Google One, a subscription service that offers expanded cloud storage, can now take advantage of a whole-phone backup solution for Android that automatically copies videos, multimedia messages (MMS), and uncompressed photos to Google's datacenters. But wait, you might say, doesn't Google already offer a free backup solution for Android? That's true, but it only covers content, select data (apps, call history, contacts, and calendar), and settings. (Only Pixel phones get native SMS backup.) And while Google's eponymous Google Photos service backs up photos and videos for free, it by default resizes pics to 16MP (original-quality photos count against your Google Account storage). Google One doesn't touch photos before uploading them, and it throws in the aforementioned text messages backup at no extra charge.

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An anonymous reader quotes a report from Politico: The U.S. government concluded within the past two years that Israel was most likely behind the placement of cellphone surveillance devices that were found near the White House and other sensitive locations around Washington, according to three former senior U.S. officials with knowledge of the matter. But unlike most other occasions when flagrant incidents of foreign spying have been discovered on American soil, the Trump administration did not rebuke the Israeli government, and there were no consequences for Israel's behavior, one of the former officials said. The miniature surveillance devices, colloquially known as "StingRays," mimic regular cell towers to fool cellphones into giving them their locations and identity information. Formally called international mobile subscriber identity-catchers or IMSI-catchers, they also can capture the contents of calls and data use. The devices were likely intended to spy on President Donald Trump, one of the former officials said, as well as his top aides and closest associates -- though it's not clear whether the Israeli efforts were successful. An Israeli Embassy spokesperson denied that Israel placed the devices and said: "These allegations are absolute nonsense. Israel doesn't conduct espionage operations in the United States, period." Furthermore, after this story was published, Israeli Prime Minister Benjamin Netanyahu denied that Israel was behind the devices. "We have a directive, I have a directive: No intelligence work in the United States, no spies," he said in a gaggle with reporters. "And it's vigorously implemented, without any exception. It [the report] is a complete fabrication, a complete fabrication."

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An anonymous reader shares a report: Manjaro may have lofty goals of becoming a successful company, but let's be honest -- users of the Linux-based operating system don't really care about that. Don't get me wrong, I am sure most members of the Linux community are rooting for the newly-formed company's success, but they are probably more interested in the excellent operating system itself. Today, Manjaro Linux 18.1.0 "Juhraya" finally becomes available for download, and it isn't without some controversy. You see, rather than just offer up LibreOffice like most distributions, Juhraya offers an alternative choice at installation -- FreeOffice. "After six months of development, version 18.1 of Manjaro Linux is now available. Juhraya offers numerous improvements, especially with regard to Office productivity applications and package management. Another significant innovation in Manjaro 18.1 is the integrated support for FlatPak and Snap packages. For this purpose, the graphical package management tool 'bauh' (formerly known as 'fpakman' ) is now available to users," says Philip Muller, Manjaro developer.

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ted_pikul writes: A team of scientists have created a device that turns the cold of space into enough electricity to power an LED light. As described in a paper published on Thursday in the journal Joule, the device is based off of a thermoelectric generator that creates electricity from the difference in temperature between a "hot side" and a "cold side." The researchers -- UCLA scientist Aaswath Raman, and Stanford scientists Wei Li and Shanhui Fan -- decided to take this idea one step further and use the ambient environment of Earth as a heat source and the cold of outer space as one gigantic cold sink. The prototype consists of four stilts supporting two plates sandwiched between a thermoelectric generator. One plate is aimed at the ground, the other at the sky. The downward-facing plate draws heat from the air around it, while the upward-facing plate is paired with an aluminum disk painted black. The disk acts as an emitter that radiates heat into space through Earth's atmosphere, cooling the plate to below ambient temperature. This effect is known as radiative cooling, Raman said, and scientists have known about the phenomenon for years. It's the reason why a window can be frosty in the morning even when last night's temperature wasn't below freezing, and, as Raman explained in a 2018 TED Talk, it's the reason ancient Persians were able to make and store ice in the desert.

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Digital dosh scorned as a threat to national sovereignty

On Thursday Facebook's Libra cryptocurrency has received a Gallic dismissal courtesy of France's finance minister.…

Five nabbed over conspiracy to commit a public nuisance

Five people have been arrested by the Metropolitan Police for threatening to fly drones around London’s Heathrow airport this Friday to protest climate change.…

Kate Marvel, writing for Scientific American: We are, I promise you, not doomed, no matter what Jonathan Franzen says. We could be, of course, if we decided we really wanted to. We have had the potential for total annihilation since 1945, and the capacity for localized mayhem for as long as societies have existed. Climate change offers the easy choice of a slow destruction through inaction like the proverbial frog in the slowly boiling pot. And there are times when the certainty of inevitability seems comforting. Fighting is exhausting; fighting when victory seems uncertain or unlikely even more so. It's tempting to retreat to a special place -- a cozy nook, a mountaintop, a summer garden -- wait for the apocalypse to run its course, and hope it will be gentle. [...] It is precisely the fact that we understand the potential driver of doom that changes it from a foregone conclusion to a choice, a terrible outcome in the universe of all possible futures. I run models through my brain; I check them with the calculations I do on a computer. This is not optimism, or even hope. Even in the best of all possible worlds, I cannot offer the certainty of safety. Doom is a possibility; it may that we have already awakened a sleeping monster that will in the end devour the world. It may be that the very fact of human nature, whatever that is, forecloses any possibility of concerted action. But I am a scientist, which means I believe in miracles. I live on one. We are improbable life on a perfect planet. No other place in the universe has nooks or perfect mountaintops or small and beautiful gardens. A flower in a garden is an exquisite thing, rooted in soil formed from old rocks broken by weather. It breathes in sunlight and carbon dioxide and conjures its food as if by magic. For the flower to exist, a confluence of extraordinary things must happen. It needs land and air and light and water, all in the right proportion, and all at the right time. Pick it, isolate it, and watch it wither. Flowers, like people, cannot grow alone.

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UK MPs have called for the government to regulate the games industry's use of loot boxes under current gambling legislation -- urging a blanket ban on the sale of loot boxes to players who are children. From a report: Kids should instead be able to earn in-game credits to unlock look boxes, MPs have suggested in a recommendation that won't be music to the games industry's ears. Loot boxes refer to virtual items in games that can be bought with real-world money and do not reveal their contents in advance. The MPs argue the mechanic should be considered games of chance played for money's worth and regulated by the UK Gambling Act. The Department for Digital, Culture, Media and Sport's (DCMS) parliamentary committee makes the recommendations in a report published today following an enquiry into immersive and addictive technologies that saw it take evidence from a number of tech companies including Fortnite maker Epic Games; Facebook-owned Instagram; and Snapchap. The committee said it found representatives from the games industry to be "wilfully obtuse" in answering questions about typical patterns of play -- data the report emphasizes is necessary for proper understanding of how players are engaging with games -- as well as calling out some games and social media company representatives for demonstrating "a lack of honesty and transparency," leading it to question what the companies have to hide.

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The amber DNA in Jurassic Park? That's you, that is

Stamping your footprints on the Moon's surface remains an impossible bucket-list ambition for practically all of us over the age of two. But for $99 you might still be able to leave a DNA footprint there.…

Spotify knows a lot about its users -- their musical tastes, their most listened-to artists and their summer anthems. Now it will also want to know where you live or to obtain your location data. It's part of an effort to detect fraud and abuse of its Premium Family program. From a report: Premium Family is a $15-a-month plan for up to six people. The only condition is that they all live at the same address. But the streaming music giant is concerned about people abusing that plan to pay as little as $2.50 for its services. So in August, the company updated its terms and conditions for Premium Family subscribers, requiring that they provide location data "from time to time" to ensure that customers are actually all in the same family. You have 30 days to cancel after the new terms went into effect, which depends on where you are. The family plan terms rolled out first on Aug. 19 in Ireland and on Sept. 5 in the US. The company tested this last year and asked for exact GPS coordinates but ended the pilot program after customers balked. Now it intends on rolling the location data requests out fully, reigniting privacy concerns and raising the question of how much is too much when it comes to your personal information.

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