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AstraZeneca has licensed Algen Biotechnologies' AI-powered gene-editing platform, AlgenBrain, to develop immune-related therapies in a deal worth up to $555 million. Reuters reports: AstraZeneca will get exclusive rights to develop and sell approved therapies, if any, that target immune system-related disorders in exchange for upfront and milestone payments to Algen. AstraZeneca has been advancing its cell and gene therapy capabilities through acquisitions and partnerships as it works towards its target of $80 billion in sales by 2030. Globally too, drugmakers are increasingly turning to artificial intelligence for drug development.
Monday's deal, however, does not include AstraZeneca buying a stake in the company, Algen CEO and co-founder Chun-Hao Huang told Reuters in an interview. "Together with AstraZeneca's deep expertise in translational science and clinical development, we aim to uncover new biological insights to accelerate the development of novel therapies," Huang said. Algen was spun out from the UC Berkeley lab where biochemist Jennifer Doudna pioneered the CRISPR technology that won her the Nobel Prize. The biotech firm's AI platform, AlgenBrain, can map genes to disease outcomes, helping the companies decide their development focus for targeted therapies.
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California biotech entrepreneur and former magician Serhat Gumrukcu has been found guilty of orchestrating the 2018 murder of his business rival Gregory Davis, who had threatened to expose Gumrukcu's fraudulent dealings. He faces sentencing in November. SFGATE reports: Seven years ago, Turkish national Serhat Gumrukcu, 42, of Los Angeles, was negotiating a multimillion-dollar biotech merger built off his work on a supposed HIV cure. The deal was put in jeopardy by a former business partner named Gregory Davis, 49, who had threatened to bring legal action against Gumrukcu for fraudulent activities relating to a previous failed oil commodities deal, the U.S. Attorney's Office said in a news release last week. Gumrukcu, a magician-turned-scientist who admitted to buying his medical degree from a Russian university, lived in a Hollywood mansion and partied with Oscar winners and movie producers, according to VTDigger. He stood to make millions from the merger of his biotech company Enochian BioSciences. [...]
In 2017, upon learning that Davis, a father of six from Danville, Vermont, could potentially spoil his fortune-making deal, Gumrukcu set in motion a hit on the former business partner. The murder-for-hire plot involved four men in total, prosecutors said. Gumrukcu had a close friend from Las Vegas, Berk Eratay, approach a third man, Aron Ethridge to find a hit man to kill Davis. The shooter, 37-year-old Montana man Jerry Banks, arrived at Davis' home on Jan. 6, 2018, in a vehicle fitted with flashing red and blue lights and posed as a deputy U.S. marshal. After abducting Davis, Banks shot him dead in the vehicle and left the body partially buried in a snowbank nearby.
Investigators soon narrowed in on Gumrukcu after discovering emails between him and Davis revealing tensions over the failed oil deal. Gumrukcu was interviewed twice by the FBI and made false statements on both occasions, federal prosecutors said. Further inspection of cellphone data, bank information and messages identified the four men involved in the kidnapping and killing of Davis.
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An anonymous reader quotes a report from BleepingComputer: The Redis security team has released patches for a maximum severity vulnerability that could allow attackers to gain remote code execution on thousands of vulnerable instances. Redis (short for Remote Dictionary Server) is an open-source data structure store used in approximately 75% of cloud environments, functioning like a database, cache, and message broker, and storing data in RAM for ultra-fast access. The security flaw (tracked as CVE-2025-49844) is caused by a 13-year-old use-after-free weakness found in the Redis source code and can be exploited by authenticated threat actors using a specially crafted Lua script (a feature enabled by default). Successful exploitation enables them to escape the Lua sandbox, trigger a use-after-free, establish a reverse shell for persistent access, and achieve remote code execution on the targeted Redis hosts.
After compromising a Redis host, attackers can steal credentials, deploy malware or cryptocurrency mining tools, extract sensitive data from Redis, move laterally to other systems within the victim's network, or use stolen information to gain access to other cloud services. "This grants an attacker full access to the host system, enabling them to exfiltrate, wipe, or encrypt sensitive data, hijack resources, and facilitate lateral movement within cloud environments," said Wiz researchers, who reported the security issue at Pwn2Own Berlin in May 2025 and dubbed it RediShell.
While successful exploitation requires attackers first to gain authenticated access to a Redis instance, Wiz found around 330,000 Redis instances exposed online, with at least 60,000 of them not requiring authentication. Redis and Wiz urged admins to patch their instances immediately by applying security updates released on Friday, "prioritizing those that are exposed to the internet." To further secure their Redis instances against remote attacks, admins can also enable authentication, disable Lua scripting and other unnecessary commands, launch Redis using a non-root user account, enable Redis logging and monitoring, limit access to authorized networks only, and implement network-level access controls using firewalls and Virtual Private Clouds (VPCs).
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Inference service launched a month before IPO filing turns out to have been a much bigger business than initially thought
Just days after announcing a $1.1 billion Series G funding round, AI chip startup Cerebras Systems pulled its S-1 IPO filing without so much as an explanation. …
Bloomberg reports (paywalled) that Apple's hardware chief John Ternus is the frontrunner to replace Tim Cook as CEO, as Cook nears retirement and prepares to transition into a board chairman role. The Economic Times reports: Cook is turning 65 next month. Chief operating officer John Williams -- once heir apparent -- has handed over the reins of day-to-day operations to Sabih Khan and is on his way out. Even as Cook steps down as CEO, he will stay involved in some capacity, likely as board chairman. [...]
While Khan and Apple's retail chief Deirdre O'Brien can run daily operations, Ternus remains the leading contender for the corner office after Cook, Gurman said. Firstly, he is 50 years old -- the same as Cook when he became CEO -- giving him over a decade to hold the office, he noted. Secondly, Apple needs a technologist instead of a sales person at the helm, considering the company's ambitions, Gurman wrote in the newsletter. While the Cupertino tech giant has managed to expand its homegrown line of chipsets, and the recently launched iPhone 17 lineup is drawing in customers, the company has struggled to find success in categories such as mixed reality, generative artificial intelligence (AI), smart homes and autonomous driving.
Ternus was in the spotlight during Apple's annual hardware event in September, which saw the launch of the iPhone 17 Air, the first major design overhaul for the smartphone family in a long time. Over the years, he has gained more responsibilities under Cook, taking calls on product roadmaps, features and strategies, overseeing matters beyond the traditional scope of a hardware engineering chief, Gurman said.
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You can't find anything bad if you don't look, right?
Medusa ransomware affiliates are among those exploiting a maximum-severity bug in Fortra's GoAnywhere managed file transfer (MFT) product, according to Microsoft Threat Intelligence.…
Police arrested 33-year-old Joseph Mayuyo after a series of online threats forced TikTok to evacuate its Culver City headquarters. TechCrunch reports: A press release from the Culver City Police Department says that TikTok employees reported receiving multiple threats, across various social media platforms, from 33-year-old Hawthorne resident Joseph Mayuyo. After an additional message threatened TikTok's Culver City headquarters, police say company security evacuated the office "out of an abundance of caution."
Police then investigated Mayuyo's home, according to the press release. During the investigation, he allegedly posted additional threatening statements, including one declaring that he would not be taken alive. Detectives obtained search and arrest warrants, and they negotiated with Mayuyo for 90 minutes before he voluntarily exited his home and was taken into custody, the police department says.
Business Insider reports that one TikTok employee described the threats as "really scary," while another was concerned that they seemed to specifically target the e-commerce department. Mayuyo's X account has reportedly been suspended for violating the platform's hateful content policy. A Medium account under his name published a post in July criticizing TikTokShop USA as a "scam."
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Prime Video bowdlerized Bond just in time for 007's special day
In more than 60 years of adventures, James Bond has faced off against villains ranging from Blofeld to Le Chiffre. But none of them has managed to do what Jeff Bezos and his henchmen did to the international superspy: take his weapons away.…
Bernie Sanders calls for a robot tax and a 32-hour work week in response
ai-pocalypse A US Senate committee led by Bernie Sanders (I-VT) has produced a report claiming that about 97 million US jobs could be lost to AI and automation over the next decade. There's just one problem: it got those figures from ChatGPT.…
An anonymous reader quotes a report from The Verge: OpenAI is introducing a way to work with apps right inside ChatGPT. The idea is that, from within a conversation with the chatbot, you can essentially tag in apps to help you complete a task while ChatGPT offers context and advice. [...]
Apps available inside ChatGPT starting today will include Booking.com, Canva, Coursera, Expedia, Figma, Spotify, and Zillow. In the "weeks ahead," OpenAI will add more apps, such as DoorDash, OpenTable, Target, and Uber. [...] Developers can access the SDK for making apps in preview starting today. Later this year, developers will be able to submit apps for review and publication, and OpenAI also plans to offer a directory for users to browse apps, according to OpenAI CEO Sam Altman. The company will share guidance about monetization "soon," Altman says. Last week, ChatGPT unveiled a new feature called "Instant Checkout" that lets users buy stuff directly through its chatbot -- "part of its overall push to integrate it with the rest of the web," reports The Verge.
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Kessler syndrome is bad; atmospheric incineration may be worse, says astrophysicist Jonathan McDowell
If you had to guess how many Starlink satellites burn up in Earth's atmosphere on an average day, how many would you pick? This isn't a trick question - SpaceX is deorbiting about one or two satellites daily, and that number is only going to grow. …
Porsche's wireless charging system will not be available on the Macan Electric and Taycan because the inductive charging plate cannot physically fit between the front suspension on those models. Dr. Maximilian Muller, Porsche's high voltage engineering lead, told The Drive during a visit to the company's Leipzig facility that the Cayenne Electric's larger dimensions create the necessary space for the charging hardware beneath the front motor. The Cayenne Electric is wider than both the Taycan and Macan Electric. The larger vehicle forced Porsche to design different suspension geometry even though it shares the PPE platform with the Macan Electric. The changes create additional packaging constraints that prevent retrofitting the wireless charging system into existing electric models.
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Since revealing Stargate in January, Altman and friends have brought about 200 MW online - they'll need at least 16 GW to claim their red and green prize
Comment AMD has issued OpenAI a warrant for roughly 10 percent of its stock. In exchange, the AI model giant will work with its partners (such as Oracle) to deploy up to 6 gigawatts' worth of AMD GPUs.…
An anonymous reader shares a report: Pay-advance apps are marketed as a way to help workers living paycheck to paycheck pay for unexpected expenses, but workers are often using the apps to manage basic expenses like groceries, rent and other needs, a new report found. The tools, consumer advocates say, can carry costs akin to those of traditional payday loans.
An analysis of anonymous data found worrisome behavior among users of the apps, including quick increases in the number of advances, advances from multiple apps at the same time and more frequent bank overdraft fees. "These findings reveal persistent patterns of financial strain that raise serious concerns about the long-term effects of these loans," said the report from the Center for Responsible Lending, a nonprofit consumer advocacy group. The group analyzed data from SaverLife, a nonprofit that promotes saving and sound financial practices among people with low or moderate incomes. The analysis found that heavy users of the apps paid $421, on average, in total loan and overdraft fees over a year, or almost triple the average paid by moderate users.
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Integrate your apps via their Apps SDK and maybe they'll send you some business
OpenAI on Monday pitched its coding tools to software developers in the hope of generating the usage and revenue necessary to recoup the vast sums it spends to create and run its AI services.…
BrianFagioli writes: Canonical has revealed the codename for Ubuntu 26.04 LTS: Resolute Raccoon. The announcement came today on X through the official @ubuntu account, continuing the tradition of pairing an adjective with an animal for each release. As an LTS version, it will be supported for five years and serve as the foundation for servers, desktops, and cloud deployments when it launches in April 2026.
While the name itself is now public, the features of Ubuntu 26.04 remain under wraps. The community will be watching closely to see which kernel it ships with, how GNOME evolves, and what improvements land for enterprise and container use. For now, fans simply have a raccoon mascot to rally around as the countdown to April begins.
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Microsoft said in a statement Monday it remains committed to developing first-party Xbox consoles. The reassurance came after rumors circulated suggesting the gaming division might abandon hardware manufacturing. The speculation gained traction following a 50% price increase for Xbox Game Pass Ultimate and retailers including Costco removing Xbox products from their shelves.
Microsoft said it is "actively investing in our future first-party consoles and devices designed, engineered and built by Xbox." The company's multi-year partnership with AMD for next-generation hardware also continues. Devices in development include the Xbox Ally range under codenames Omni and Horseman, according to Windows Central. Xbox Series X and Series S production has also not stopped, the report added.
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An anonymous reader shares a report: OpenAI CEO Sam Altman said Monday that ChatGPT has reached 800 million weekly active users, marking an increase of adoption among consumers, developers, enterprises, and governments. ChatGPT's impressive growth comes as OpenAI is on a race to secure as many AI chips and build as much AI infrastructure as possible. In August, OpenAI said it was on the cusp of reaching 700 million weekly active users, already an increase from 500 million weekly active users at the end of March.
"Today, 4 million developers have built with OpenAI," Altman said. "More than 800 people use ChatGPT every week, and we process over 6 billion tokens per minute on the API. Thanks to all of you, AI has gone from something people build play with to something people build with every day." Altman made the announcement during the keynote presentation for OpenAI's Dev Day, which also included announcement for new tools for building apps inside of ChatGPT, as well as constructing more complex agentic systems. "This will enable a new generation of apps that are interactive, adaptive, and personalized, that you can chat with," Altman said.
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An anonymous reader shares a report: Tucked in the foothills of Tennessee's Smoky Mountains is a factory that has figured out a way to manufacture in America that's cheaper, quicker and better. It's the home of a famous American writing implement: the Sharpie marker. Pen barrels whirl along automated assembly lines that rapidly fill them with ink. At least half a billion Sharpie markers are churned out here every year, each one made of six parts. Only the felt tip is imported, from Japan.
It didn't used to be this way. Back in 2018, many Sharpies were made abroad. That's when Chris Peterson, who was the CFO of Sharpie maker Newell Brands challenged his team to answer a question: How could they keep Newell from becoming obsolete compared with factories in Asia? "I felt like we had an opportunity to dramatically improve our U.S. manufacturing," he said. Peterson is now the CEO. And these days, most Sharpies -- in all 93 colors -- are made at this 37-year-old factory. Newell did it without reducing the employee count, and without raising prices. But to get to this place took close to $2 billion in investments across the company, thousands of hours of training and a total overhaul of the production process. The result is a playbook for making low-cost, high-volume products domestically, albeit one that requires long-term planning and a lot of investment.
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No evidence of exploitation … yet
A 13-year-old critical flaw in Redis servers, rated a perfect 10 out of 10 in severity, can let an authenticated user trigger remote code execution.…
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